An ozone injection into the knee can soothe pain and improve quality of life for people with knee osteoarthritis, a randomized controlled trial suggests.
“When I saw the results I was very surprised,” said Virginia Fernandes Moça Trevisani, PhD, from the Federal University of Sao Paulo, who presented the finding here at the American College of Rheumatology (ACR) 2015 Annual Meeting.
Ozone appears to inhibit prostaglandins and cytokines and reduce oxidative stress, she told Medscape Medical News.
It has been used in Europe for many years in the treatment of cancer, AIDS, caries, rheumatoid arthritis, and a variety of other ailments. However, it is not approved for clinical use in Brazil or in the United States, and the only studies in osteoarthritis have been case reports, Dr Trevisani explained.
American College of Rheumatology (ACR)